Real world evidence studies in primary care
The evidence for pharmaceutical interventions in any chronic disease comes mostly from secondary care or tertiary care in highly selected patients for research. However, in almost all countries, chronic diseases are treated in primary care. Since patients with chronic diseases in secondary care are often referred for their complexity, we know little about the large group of ordinary patients and his reaction on treatment in real life. This means that there is a lack of evidence regarding the treatment of the ordinary patient in primary care.
The GPRI aims to improve the lives of patients with chronic diseases by facilitating and participating in studies that investigate the long term effect of pharmaceutical products for chronic diseases in primary care. The Netherlands are particularly well suited for this, with a well-developed primary care system with listed patients and good electronic patient registration systems.
The GPRI is based on the experience and knowledge of the GRIAC primary care research group who have extended experience in developing primary care tools such as the Clinical COPD Questionnaire (CCQ), conducting clinical trials, and performing health economic studies. The founder and managing director of the GPRI, Professor Dr. Thys van der Molen, has published more than 200 international articles regarding primary care research.
The organization model of the GPRI is based on the participation of independent practices in the region, with highly motivated and well trained General Practitioners and their staff.
All practices have staff that completed Good Clinical Practice research courses and work according to the Helsinki rules. Participating practices are obliged to deliver and are selected because they have a track record of performing studies. To ensure uniformity, we update participating practices with regular newsletters and seminars. The GPRI has 50,000 patients we can include in research.
Diverse and direct
+The GPRI is ready to implement studies within primary care common chronic diseases such as:
oChronic heart disease
oUrinary tract disease.
+Start of inclusion of patients should take place no more than 14 days after necessary paper work has been
+Inclusion time should be limited to
12 weeks for each study.
If you are interested to participate in
this initiative, please contact:
Prof. Thys van der Molen, email@example.com or visit us
+ The GPRI is a primary care research institute with 50,000 GP patients
+ We perform real world primary care studies in all major chronic diseases
+ Only 12 week overall inclusion time
+ Staff with extended academic, business and research experience
Aim: To perform real world evidence studies
in primary care
address Zuiderkuipen 8 | 9711 HR Groningen | the Netherlands | firstname.lastname@example.org