Does mixing inhaler devices lead to unchecked inhaler technique errors in patients with COPD? Findings from the cross-sectional observational MISMATCH study.

BMJ Open Respir Res. 2023 Dec;10(1)

Patients with chronic obstructive pulmonary disease (COPD) may be prescribed multiple inhalers that require different techniques for optimal...

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Identifying critical inhalation technique errors in Dry Powder Inhaler use in patients with COPD based on the association with health status and exacerbations: findings from the multi-country cross-sectional observational PIFotal study.

BMC Pulm Med. 2023 Aug;23(1):302

Correct inhaler use depends on a complex interplay of factors, including device preparation and generating sufficient inspiratory flow. It is...

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Development of a tool to detect small airways dysfunction in asthma clinical practice.

Eur Respir J. 2023 Mar;61(3)

Small airways dysfunction (SAD) in asthma is difficult to measure and a gold standard is lacking. The aim of this study was to develop a simple tool...

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Factors associated with health status and exacerbations in COPD maintenance therapy with dry powder inhalers.

NPJ Prim Care Respir Med. 2022 May;32(1):18

The study aimed to determine the associations of Peak Inspiratory Flow (PIF), inhalation technique and adherence with health status and exacerbations...

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European Respiratory Society guidelines for the diagnosis of asthma in adults.

Eur Respir J. 2022 Sep;60(3)

Although asthma is very common, affecting 5-10% of the population, the diagnosis of asthma in adults remains a challenge in the real world, which...

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Assessment of the role of small airway dysfunction in relation to exacerbation risk in patients with well controlled asthma (ATLANTIS): an observational study.

Lancet Respir Med. 2025 Sep;

Recent surveys suggest that asthma remains inadequately controlled in more than 50% of adults with asthma despite guideline-based standard therapy....

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Phase 2a, Randomized Trial of Mitiperstat Versus Placebo in Patients with COPD at High Risk of Exacerbation (CRESCENDO).

Int J Chron Obstruct Pulmon Dis. 2025 ;20:3305

Neutrophilic inflammation, a key feature of chronic obstructive pulmonary disease (COPD), is associated with exacerbations and poor outcomes....

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Feasibility, quality and added value of unsupervised at-home spirometry in primary care.

NPJ Prim Care Respir Med. 2025 Sep;35(1):42

At-home spirometry could provide added value for the diagnosis and monitoring of obstructive pulmonary disease in primary care. However, it is...

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Expert Perspectives on Next Generation Health Guidelines: How to Integrate RWE in EBM.

Pragmat Obs Res. 2025 ;16:169

Integrating real-world evidence (RWE) into evidence-based medicine (EBM) enhances healthcare decision-making. RWE provides insights into the...

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Detecting Small Airways Dysfunction in Asthma: Rationale, Findings, and Future of ATLANTIS.

J Allergy Clin Immunol Pract. 2025 Aug;

Small airway dysfunction (SAD) is both common and clinically relevant in patients with asthma. However, there is no recognized "gold standard"...

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Adherence to inhaled corticosteroid medications after an asthma exacerbation and the risk of subsequent exacerbations.

Ann Allergy Asthma Immunol. 2025 Aug;

Data on the duration of improved adherence to controller medications after an exacerbation and its impact on asthma outcomes are inconsistent.

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The Burden of COPD with Type 2 Inflammation in North-West Continental Europe.

Int J Chron Obstruct Pulmon Dis. 2025 ;20:2767

Chronic obstructive pulmonary disease (COPD) is a complex and heterogeneous disease that places a huge burden on patients, health systems and...

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