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Assessment of the role of small airway dysfunction in relation to exacerbation risk in patients with well controlled asthma (ATLANTIS): an observational study.

Recent surveys suggest that asthma remains inadequately controlled in more than 50% of adults with asthma despite guideline-based standard therapy....

Phase 2a, Randomized Trial of Mitiperstat Versus Placebo in Patients with COPD at High Risk of Exacerbation (CRESCENDO).

Neutrophilic inflammation, a key feature of chronic obstructive pulmonary disease (COPD), is associated with exacerbations and poor outcomes....

Feasibility, quality and added value of unsupervised at-home spirometry in primary care.

At-home spirometry could provide added value for the diagnosis and monitoring of obstructive pulmonary disease in primary care. However, it is...

Expert Perspectives on Next Generation Health Guidelines: How to Integrate RWE in EBM.

Integrating real-world evidence (RWE) into evidence-based medicine (EBM) enhances healthcare decision-making. RWE provides insights into the...

Detecting Small Airways Dysfunction in Asthma: Rationale, Findings, and Future of ATLANTIS.

Small airway dysfunction (SAD) is both common and clinically relevant in patients with asthma. However, there is no recognized "gold standard"...

Adherence to inhaled corticosteroid medications after an asthma exacerbation and the risk of subsequent exacerbations.

Data on the duration of improved adherence to controller medications after an exacerbation and its impact on asthma outcomes are inconsistent.

The Burden of COPD with Type 2 Inflammation in North-West Continental Europe.

Chronic obstructive pulmonary disease (COPD) is a complex and heterogeneous disease that places a huge burden on patients, health systems and...

Using 21 century diagnostics to overcome barriers for lung function testing in primary care: it is time to consider oscillometry.

Obstructive airways diseases, including asthma and COPD as the most commonly encountered respiratory diseases in primary care, are both diagnosed by...

ReferID and AsthmaOptimiser: Digital tools to support structured asthma consultations in primary care.

Globally, many patients with severe or uncontrolled asthma receive inadequate treatment, which contributes to significant disease burden, healthcare...

Holistic Impact of CKD: A Clinical, Economic, and Environmental Analysis by IMPACT CKD.

Chronic kidney disease (CKD) is a growing global health problem driven by aging and the rise of comorbidities, including diabetes and hypertension....

Validating the Finnish Child and Teen Versions of the Food Allergy Quality of Life Questionnaire.

CodeX effectively identifies high-risk patients with asthma or COPD in Dutch primary care, supporting guideline-driven treatment.

Prevention of lung attacks (LAs)/exacerbation is an important treatment goal in both asthma and chronic obstructive pulmonary disease (COPD)....